Description

Thiophene, 2-[1-[(Trimethylsilyl)oxy]ethyl]- is a specialized organosilicon-thiophene derivative, a key building block in advanced organic synthesis. This compound is valued for its role as a protected functional group intermediate, enabling precise molecular construction in sensitive applications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the multi-step synthesis of complex drug candidates, particularly those containing thiophene or heterocyclic scaffolds.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, where the thiophene moiety can contribute to biological activity.
• Organic Light-Emitting Diodes (OLEDs): Used as a precursor in the synthesis of novel organic semiconductors and electron-transport materials for display technologies.
• Material Science: Acts as a building block for polymers and advanced materials requiring specific electronic or photophysical properties.
• Cross-Coupling Reactions: The silyl-protected hydroxyl group makes it a suitable substrate for palladium-catalyzed reactions like Suzuki or Stille couplings.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry and catalysis.

Basic Information

Product Name	Thiophene, 2-[1-[(Trimethylsilyl)oxy]ethyl]-
CAS No.	959087-59-3
Molecular Formula	C9H16OSSi
Molecular Weight	200.37 g/mol
Synonyms	2-(1-Trimethylsiloxyethyl)thiophene; 1-(2-Thienyl)ethanol trimethylsilyl ether; 2-(1-Hydroxyethyl)thiophene TMS ether; 2-Acetylthiophene O-trimethylsilyl oxime (related derivative); TMS-protected 2-(1-hydroxyethyl)thiophene; α-(Trimethylsiloxy)ethyl thiophene
EINECS	Contact for details

Quality Control

Our production of Thiophene, 2-[1-[(Trimethylsilyl)oxy]ethyl]- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Identity and purity are confirmed via advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.