Description

Propanamide, n-[(1,1-Dimethylethyl)dimethylsilyl]- is a specialized organosilicon-protected amide derivative, serving as a valuable synthetic intermediate in advanced organic synthesis. Its primary value lies in its role as a protected functional group, enabling complex multi-step reactions where the amide moiety must be shielded from reactive conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable building blocks for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those containing amide functionalities that require temporary protection.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where specific amide groups are integral to the molecule's activity.
• Peptide Chemistry: Acts as a protected amino acid derivative or coupling agent in the synthesis of modified peptides and peptidomimetics.
• Material Science Research: Employed in the creation of novel silicon-containing polymers and hybrid organic-inorganic materials.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes and labeled compounds for biochemical studies.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Propanamide, n-[(1,1-Dimethylethyl)dimethylsilyl]-
CAS No.	958998-86-2
Molecular Formula	C9H21NOSi
Molecular Weight	187.36 g/mol
Synonyms	N-(tert-Butyldimethylsilyl)propanamide; N-(TBDMS)propanamide; Propanamide, N-[(1,1-dimethylethyl)dimethylsilyl]-; tert-Butyldimethylsilyl propanamide; TBDMS-propanamide; N-(tert-Butyldimethylsilyl)propionamide; Propionamide, N-(tert-butyldimethylsilyl)-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our advanced intermediates. Each batch of Propanamide, n-[(1,1-Dimethylethyl)dimethylsilyl]- is analyzed to ensure high chemical purity and identity confirmation, typically exceeding 95% by HPLC or GC analysis. Our quality system is designed to meet the exacting standards of GMP-compliant synthesis environments. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 95.0%
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.