Description

3-Quinolinecarbonitrile, 6-Bromo-4-Hydroxy- is a high-purity brominated quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in creating novel active ingredients for crop protection products, leveraging its halogenated quinoline core.
• Material Science Precursor: Serves as a starting material for the development of organic semiconductors, ligands for metal complexes, and advanced polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry to explore structure-activity relationships (SAR) and develop molecular probes.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-Quinolinecarbonitrile, 6-Bromo-4-Hydroxy-
CAS No.	958649-15-5
Molecular Formula	C10H5BrN2O
Molecular Weight	249.07 g/mol
Synonyms	6-Bromo-4-hydroxyquinoline-3-carbonitrile; 4-Hydroxy-6-bromoquinoline-3-carbonitrile; 6-Bromo-4-hydroxy-3-cyanoquinoline; 6-Bromo-4-hydroxy-3-quinolinecarbonitrile; 958649-15-5; 6-Bromo-4-hydroxyquinoline-3-carbonitrile; 4-Hydroxy-6-bromo-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarbonitrile, 6-Bromo-4-Hydroxy- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.