Description

3-Pyridinecarboxylic Acid, 4-Chloro-5-Hydroxy- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines a carboxylic acid group with chloro and hydroxy substituents on the pyridine ring, enabling precise chemical modifications. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, metal-organic frameworks (MOFs), and other advanced materials.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 4-Chloro-5-Hydroxy-
CAS No.	958294-52-5
Molecular Formula	C6H4ClNO3
Molecular Weight	173.55 g/mol
Synonyms	4-Chloro-5-hydroxynicotinic acid; 5-Hydroxy-4-chloronicotinic acid; 4-Chloro-5-hydroxy-3-pyridinecarboxylic acid; 4-Chloro-5-hydroxypyridine-3-carboxylic acid; 3-Carboxy-4-chloro-5-hydroxypyridine; 4-Chloro-5-hydroxy-pyridine-3-carboxylic acid; 4-Chloro-5-hydroxynicotinate
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 4-Chloro-5-Hydroxy- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.