Description

5-Carbamoylthiophene-2-Boronic Acid Pinacol Ester, 96% is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its stability and reactivity as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and advanced functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing thiophene and biaryl motifs for therapeutic applications.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, leveraging its boronic ester functionality for structural diversification.
• Material Science Research: Serves as a building block for constructing organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic research.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds with high efficiency and selectivity.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	5-Carbamoylthiophene-2-Boronic Acid Pinacol Ester, 96%
CAS No.	957344-92-2
Molecular Formula	C11H16BNO3S
Molecular Weight	253.13 g/mol
Synonyms	5-Carbamoyl-2-thienylboronic acid pinacol ester; 2-(5-Carbamoylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Carbamoylthiophene-2-boronic acid pinacol ester; Thiophene-5-carboxamide-2-boronic acid pinacol ester; 2-(5-Aminocarbonyl-2-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 5-Carbamoylthiophene-2-boronate; 957344-92-2
EINECS	Contact for details

Quality Control

Our 5-Carbamoylthiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), residual solvents, and related substances is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.