Description

1-[(1-Methyl-1H-Pyrazol-4-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct sulfonyl piperidine carboxylic acid structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small molecule therapeutics targeting a range of disease pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for kinase inhibitors and other enzyme-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Protease Inhibitor Development: The sulfonyl piperidine scaffold is valuable in designing molecules that interact with protease active sites.
• Chemical Biology Probes: Serves as a precursor for creating tool compounds used to study biological pathways and validate drug targets.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, non-commercial compounds for client R&D.
• Library Synthesis: Used to generate diverse compound libraries for high-throughput screening (HTS) in drug discovery campaigns.

Basic Information

Product Name	1-[(1-Methyl-1H-Pyrazol-4-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid
CAS No.	957301-79-0
Molecular Formula	C10H15N3O4S
Molecular Weight	273.31 g/mol
Synonyms	1-[(1-Methyl-1H-pyrazol-4-yl)sulfonyl]piperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-; 1-(1-Methyl-1H-pyrazole-4-sulfonyl)piperidine-3-carboxylic acid; Piperidine-3-carboxylic acid, 1-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-; 957301-79-0; 1-(1-Methyl-1H-pyrazol-4-ylsulfonyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-[(1-Methyl-1H-Pyrazol-4-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.