Description

2-(Piperazin-1-yl)pyridine-4-boronic acid, pinacol ester is a high-value, multifunctional boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, particularly those containing complex heterocyclic scaffolds like piperazine and pyridine.
• Agrochemical Research: Used in creating novel active ingredients for crop protection products, leveraging its ability to introduce the pyridine-piperazine motif.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed in the development of chemical probes and inhibitors that target specific enzymes or biological pathways.
• Catalyst & Ligand Development: The structure can be utilized to develop novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise, complex molecular architectures.

Basic Information

Product Name	2-(Piperazin-1-yl)pyridine-4-boronic acid, pinacol ester
CAS No.	957198-31-1
Molecular Formula	C15H24BN3O2
Molecular Weight	289.19 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(piperazin-1-yl)pyridine; 2-(Piperazin-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Piperazin-1-ylpyridine-4-boronic acid pinacol ester; Pyridine, 2-(1-piperazinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-(1-Piperazinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-(Piperazin-1-yl)pyridine-4-boronic acid, pinacol ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous demands of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.