Description

3-Chloro-2-(4-Morpholino)Pyridine-4-Boronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex heterocyclic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysis, and novel polymers.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Fundamental reagent in research laboratories for methodological development and exploring new chemical space in medicinal and synthetic chemistry.

Basic Information

Product Name	3-Chloro-2-(4-Morpholino)Pyridine-4-Boronic Acid Pinacol Ester
CAS No.	957198-28-6
Molecular Formula	C15H20BClN2O3
Molecular Weight	322.60 g/mol
Synonyms	3-Chloro-2-morpholinopyridine-4-boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[3-chloro-2-(morpholin-4-yl)pyridin-4-yl]-1,3,2-dioxaborolane; 2-(3-Chloro-2-morpholinopyridin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Chloro-2-(morpholin-4-yl)isonicotinic acid pinacol boronate; PINACOL 3-CHLORO-2-MORPHOLINOPYRIDINE-4-BORONATE; 957198-28-6; Boronic acid, B-[3-chloro-2-(4-morpholinyl)-4-pyridinyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(4-Morpholino)Pyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance in critical coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening a new container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.