Description

[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Carbamic Acid 4-Nitrophenyl Ester is a high-value, multifunctional chemical building block that combines a protected boronic acid ester with a carbamate-activated phenol. This compound matters for its role as a key synthetic intermediate, enabling the construction of complex molecules through versatile cross-coupling and functional group transformations. It is primarily needed by researchers and manufacturers in the pharmaceutical and advanced materials sectors for developing active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel biaryl compounds targeted in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging its boronate ester functionality for structural diversification.
• Organic Electronics: Serves as a building block for creating conjugated polymers and small molecules used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Material Science Research: Employed in the synthesis of metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) due to its ability to act as a linker.
• Chemical Biology Probes: Utilized to develop activity-based probes and labeling agents for studying enzyme function and protein interactions.
• Polymer Modification: Acts as a functional monomer or post-polymerization modification agent to introduce boronate or carbamate groups into polymer chains.

Basic Information

Product Name	[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Carbamic Acid 4-Nitrophenyl Ester
CAS No.	957198-19-5
Molecular Formula	C19H21BN2O5
Molecular Weight	368.19 g/mol
Synonyms	4-Nitrophenyl N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate; 4-Nitrophenyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate; (4-((4-Nitrophenoxy)carbonylamino)phenyl)boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamic acid 4-nitrophenyl ester; PINACOL (4-((4-NITROPHENOXY)CARBONYLAMINO)PHENYL)BORONATE
EINECS	Contact for details

Quality Control

Our production of [4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Carbamic Acid 4-Nitrophenyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.