Description

1-(5-Chloro-2-(Trifluoromethyl)Benzyl)-7-(6-(4-Methylpiperazin-1-Yl)Pyridin-3-Yl)-1,2,3,4-Tetrahydropyrido[2,3-B]Pyrazine is a sophisticated heterocyclic organic compound of significant interest in advanced pharmaceutical research and development. This molecule is a key synthetic intermediate or potential active pharmaceutical ingredient (API) due to its complex structure featuring a tetrahydropyridopyrazine core with trifluoromethyl and piperazine substituents. It is primarily sought by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the discovery of novel therapeutics, particularly in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors for cancer therapy.
• Preclinical Studies: Employed in pharmacological and toxicological evaluations during early-stage drug discovery.
• Chemical Reference Standard: Acts as a high-purity standard for analytical method development and quality control in API manufacturing.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Assays: Applied in vitro to study specific biological target interactions and mechanisms of action.

Basic Information

Product Name	1-(5-Chloro-2-(Trifluoromethyl)Benzyl)-7-(6-(4-Methylpiperazin-1-Yl)Pyridin-3-Yl)-1,2,3,4-Tetrahydropyrido[2,3-B]Pyrazine
CAS No.	957194-91-1
Molecular Formula	C26H26ClF3N6
Molecular Weight	514.98 g/mol
Synonyms	1-[(5-Chloro-2-(trifluoromethyl)phenyl)methyl]-7-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine; UNII-2Q8Q5V3Y1Q; 2Q8Q5V3Y1Q; 1-(5-Chloro-2-(trifluoromethyl)benzyl)-7-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine; BDBM50164957; CHEMBL3185145; AKOS025147064; ZINC000103486757
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical use. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system supports the stringent requirements of GMP-grade manufacturing for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere at lower temperatures (-20°C). Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0% (Area Percent)
Purity (HPLC, Chiral)	Contact for details
Water Content (KF)	≤ 1.0% w/w
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.