Description

Spiro[6H-Cyclopenta[B]Pyridine-6,3'-[3H]Pyrrolo[2,3-B]Pyridin]-2'(1'H)-One, 3-Amino-5,7-Dihydro- is a complex spirocyclic heterocyclic compound featuring fused pyridine and pyrrolopyridine rings. This advanced chemical intermediate is valued for its unique three-dimensional molecular architecture, which is critical for imparting specific biological activity and binding properties in pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, rigid spiro scaffold.
• Chemical Biology Probes: Acts as a core structure for developing selective enzyme inhibitors or receptor modulators in biochemical assays.
• Organic Synthesis: Employed in advanced organic synthesis to construct complex polyheterocyclic systems for material science or agrochemical research.
• Preclinical Development: Utilized in the production of compounds for pharmacokinetic, pharmacodynamic, and toxicology studies.

Basic Information

Product Name	Spiro[6H-Cyclopenta[B]Pyridine-6,3'-[3H]Pyrrolo[2,3-B]Pyridin]-2'(1'H)-One, 3-Amino-5,7-Dihydro-
CAS No.	957122-44-0
Molecular Formula	C14H12N4O
Molecular Weight	252.27 g/mol
Synonyms	3-Amino-5,7-dihydrospiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridin]-2'(1'H)-one; 3-Amino-1'H-spiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-2'-one; 957122-44-0; Spiro(cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine) derivative; 3-Amino-spiro[cyclopentapyridine-pyrrolopyridin]-one.
EINECS	Contact for details

Quality Control

Our Spiro[6H-Cyclopenta[B]Pyridine-6,3'-[3H]Pyrrolo[2,3-B]Pyridin]-2'(1'H)-One, 3-Amino-5,7-Dihydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.