Description

n-(4-Chloro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a protected boronic acid, offering enhanced stability and solubility for cross-coupling reactions, which are fundamental to pharmaceutical and advanced material development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for constructing complex molecular architectures. The CAS number for this compound is 957063-08-0.

Application

This versatile boronic ester is primarily employed as a key synthetic intermediate. Its applications include:

• Pharmaceutical Intermediate: Serving as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by enabling the formation of complex biaryl structures.
• Material Science: Facilitating the creation of organic electronic materials, such as those used in OLEDs and organic photovoltaics, through controlled polymerization and functionalization.
• Chemical Biology & Proteomics: Acting as a handle for bioconjugation and the development of molecular probes and inhibitors.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	n-(4-Chloro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide
CAS No.	957063-08-0
Molecular Formula	C16H23BClNO3
Molecular Weight	323.62 g/mol
Synonyms	N-[4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide; 2-Acetamido-5-chlorophenylboronic acid pinacol ester; 4-Chloro-2-(N-acetylamino)phenylboronic acid pinacol ester; Acetamide, N-[4-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 957063-08-0; BRN 15402135
EINECS	Contact for details

Quality Control

Our n-(4-Chloro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates to support our clients' regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.