Description

4,4,5,5-Tetramethyl-2-(2-Methyl-5-Nitrophenyl)-1,3,2-Dioxaborolane CAS NO 957062-84-9 is a high-purity, functionalized boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Building block for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and enzyme inhibitors for target validation studies.
• Academic & Contract Research: Fundamental reagent for methodological development in cross-coupling catalysis and new reaction discovery.
• Fine Chemical Production: Enables the scalable, efficient synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2-Methyl-5-Nitrophenyl)-1,3,2-Dioxaborolane
CAS No.	957062-84-9
Molecular Formula	C14H20BNO4
Molecular Weight	277.13 g/mol
Synonyms	2-Methyl-5-nitrophenylboronic acid pinacol ester; (2-Methyl-5-nitrophenyl)boronic acid pinacol ester; 2-(2-Methyl-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Nitro-2-methylbenzeneboronic acid pinacol ester; Pinacol (2-methyl-5-nitrophenyl)boronate; 2-Methyl-5-nitrobenzeneboronic acid pinacol ester; 957062-84-9
EINECS	Contact for details

Quality Control

Every batch of our 4,4,5,5-Tetramethyl-2-(2-Methyl-5-Nitrophenyl)-1,3,2-Dioxaborolane undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.