Description

2-(Methoxycarbonyl)-4-Pyridineboronic Acid, Pinacol Ester is a high-purity, protected boronic acid ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and functional organic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine cores.
• Agrochemical Research: Used in the discovery and development of novel herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant boronate reagent for forming carbon-carbon bonds between aryl/heteroaryl groups under mild conditions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Material Science: A building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its conjugated pyridine system.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and bioconjugation reagents for studying biological systems.

Basic Information

Product Name	2-(Methoxycarbonyl)-4-Pyridineboronic Acid, Pinacol Ester
CAS No.	957062-72-5
Molecular Formula	C14H18BNO4
Molecular Weight	275.11 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinic acid methyl ester; Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate; 2-Carbomethoxy-4-pyridylboronic acid pinacol ester; Methyl 4-(pinacolatoboryl)picolinate; 4-Pyridineboronic acid, 2-(methoxycarbonyl)-, pinacol ester; 2-Methoxycarbonyl-4-pyridineboronic acid pinacol ester; 4-Borono-2-picolinic acid methyl ester pinacol cyclic ester
EINECS	Contact for details

Quality Control

Every batch of 2-(Methoxycarbonyl)-4-Pyridineboronic Acid, Pinacol Ester undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive cross-coupling applications. Our quality assurance protocols include comprehensive analysis by NMR (1H, 13C, 11B), HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with relevant regulatory frameworks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.