Description

trans-4-Hydroxycyclohexyl 4-Boronobenzamide is a high-purity, advanced pharmaceutical intermediate featuring a unique boronic acid derivative structure. This compound is specifically engineered for use in sophisticated cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are critical for constructing complex molecules in modern drug discovery. It is an essential building block for medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries, enabling the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Utilized in palladium-catalyzed carbon-carbon bond formation to create complex biaryl structures central to many drug molecules.
• Medicinal Chemistry Research: Enables the exploration of new chemical space and the development of drug candidates in high-throughput screening libraries.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand for Catalyst Systems: Can be employed in the development of novel catalytic systems for organic synthesis.
• Material Science Precursor: Serves as a monomer or precursor for advanced organic electronic materials and polymers.

Basic Information

Item	Details
Product Name	trans-4-Hydroxycyclohexyl 4-Boronobenzamide
CAS No.	957062-70-3
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	4-(trans-4-Hydroxycyclohexylcarbamoyl)phenylboronic Acid; (4-((trans-4-Hydroxycyclohexyl)carbamoyl)phenyl)boronic Acid; 4-Boronobenzamide, N-(trans-4-hydroxycyclohexyl)-; trans-N-(4-Hydroxycyclohexyl)-4-boronobenzamide; B-[4-[[(1r,4r)-4-Hydroxycyclohexyl]carbamoyl]phenyl]boronic Acid; 957062-70-3; Boronic Acid Derivative Intermediate
EINECS	Contact for details

Quality Control

Our trans-4-Hydroxycyclohexyl 4-Boronobenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.