Description

3-Chloro-2-Methoxypyridin-4-Ylboronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and scalable methods for creating novel pyridine-containing structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine moiety for enhanced biological activity.
• Material Science Research: Employed in the creation of organic electronic materials, including ligands for OLEDs and charge-transport materials.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of molecular probes and inhibitors for enzyme studies.
• Catalyst Ligand Development: Serves as a starting material for synthesizing novel bidentate or tridentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs engaged in producing bespoke organic compounds for client projects.

Basic Information

Product Name	3-Chloro-2-Methoxypyridin-4-Ylboronic Acid
CAS No.	957060-88-7
Molecular Formula	C6H7BClNO3
Molecular Weight	187.39 g/mol
Synonyms	(3-Chloro-2-methoxypyridin-4-yl)boronic acid; 3-Chloro-2-methoxy-4-pyridineboronic acid; 4-Borono-3-chloro-2-methoxypyridine; 2-Methoxy-3-chloropyridine-4-boronic acid; 957060-88-7; 3-Chloro-2-methoxy-4-pyridinylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Methoxypyridin-4-Ylboronic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/NMR), residual solvent content, and boronic acid assay.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C under an inert atmosphere (argon or nitrogen) to prevent oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will lead to decomposition. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Boronic Acid)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.