Description

3-Boronobenzyl Chloride is a versatile bifunctional organic building block, combining a reactive benzyl chloride group with a boronic acid/ester functionality. This dual reactivity makes it a critical intermediate for constructing complex molecular architectures via cross-coupling reactions and subsequent functional group transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific boronic acid derivatives.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics, where precise boron incorporation is needed.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to the orthogonal reactivity of the chloride and boronate groups.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Boronobenzyl Chloride
CAS No.	957035-15-3
Molecular Formula	C7H8BClO2 (for boronic acid form)
Molecular Weight	170.40 g/mol (for boronic acid form)
Synonyms	(3-Chloromethylphenyl)boronic acid; 3-(Chloromethyl)benzeneboronic acid; m-(Chloromethyl)phenylboronic acid; 3-Boronobenzylchloride; Benzeneboronic acid, 3-(chloromethyl)-; 957035-15-3; B-(3-Chloromethylphenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 3-Boronobenzyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and meet the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.