Description

4-(Methylsulfonyloxy)Phenylboronic Acid is a specialized organoboron compound featuring a phenylboronic acid core functionalized with a methylsulfonyloxy (mesylate) group. This unique bifunctional structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules via cross-coupling reactions.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boronic acid reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures.
• Pharmaceutical Intermediate: Critical for the research and production of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems.
• Material Science Research: Employed in the synthesis of organic electronic materials, polymers, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for modifying biomolecules or creating sensors due to the reactivity of the boronic acid group.

Basic Information

Product Name	4-(Methylsulfonyloxy)Phenylboronic Acid
CAS No.	957035-04-0
Molecular Formula	C7H9BO5S
Molecular Weight	216.02 g/mol
Synonyms	4-(Methanesulfonyloxy)benzeneboronic acid; [4-(Methylsulfonyloxy)phenyl]boronic acid; 4-Hydroxyphenylboronic acid mesylate ester; B-[4-[(Methylsulfonyl)oxy]phenyl]boronic acid; 4-Mesyloxyphenylboronic Acid; p-(Methylsulfonyloxy)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-(Methylsulfonyloxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance for critical synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.