Description

Methyl 3-(3-Boronobenzoylamino)Propionate is a specialized boronic acid ester derivative that serves as a valuable synthetic intermediate. Its molecular structure, featuring both a boronate ester and an amino acid ester moiety, makes it a versatile building block for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling reactions and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a boronic acid handle for bioconjugation or cross-coupling.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as an organoboron coupling partner for the formation of carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
• Medicinal Chemistry & Drug Discovery: Employed in high-throughput screening and the development of novel drug candidates, especially in oncology and CNS research.
• Agrochemical Synthesis: Serves as a building block for creating advanced crop protection agents and herbicides.
• Material Science Research: Used in the development of organic electronic materials, polymers, and ligands for catalysis.
• Bioconjugation & Probe Development: Facilitates the labeling and modification of biomolecules for diagnostic and research purposes.

Basic Information

Product Name	Methyl 3-(3-Boronobenzoylamino)Propionate
CAS No.	957034-72-9
Molecular Formula	C11H14BNO4
Molecular Weight	235.05 g/mol
Synonyms	3-[(3-Boronobenzoyl)amino]propanoic acid methyl ester; Methyl 3-[(3-boronobenzoyl)amino]propanoate; 3-Aminopropionic acid, N-(3-boronobenzoyl)-, methyl ester; 3-Borono-N-(2-methoxy-2-oxoethyl)benzamide; (3-((Methoxycarbonyl)ethylcarbamoyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our Methyl 3-(3-Boronobenzoylamino)Propionate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our analytical methods (including NMR, HPLC, and LC-MS) are validated to provide reliable specifications for our customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Solubility	Soluble in DMSO, DMF; partially soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.