Description

4-Methylamino-3-Nitrophenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative, serving as a crucial protected intermediate for Suzuki-Miyaura cross-coupling reactions. Its primary value lies in enabling the efficient construction of complex biaryl and heterobiaryl structures, which are foundational scaffolds in advanced material and pharmaceutical research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing complex aryl-aryl linkages.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and organic photovoltaics, via polymerization or small-molecule synthesis.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the creation of molecular probes for diagnostic and research applications.
• Academic & Contract Research: A staple reagent in university and CRO laboratories for methodological development and exploring new chemical space.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	4-Methylamino-3-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	956821-93-5
Molecular Formula	C13H19BN2O4
Molecular Weight	278.11 g/mol
Synonyms	4-(Methylamino)-3-nitrophenylboronic acid pinacol ester; 2-(4-Methylamino-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methylamino-3-nitrobenzeneboronic acid pinacol ester; Pinacol [4-(Methylamino)-3-nitrophenyl]boronate; 3-Nitro-4-(methylamino)phenylboronic acid pinacol ester; Boronic acid, B-[4-(methylamino)-3-nitrophenyl]-, 1,1-dimethylethyl ester; CAS 956821-93-5
EINECS	Contact for details

Quality Control

Every batch of 4-Methylamino-3-Nitrophenylboronic Acid, Pinacol Ester is manufactured and tested under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.