Description

2-(1H-Pyrazol-1-Yl)Isonicotinonitrile is a high-purity heterocyclic building block featuring a pyrazole ring linked to an isonicotinonitrile core. This compound matters as a critical intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of novel molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Chemical Biology: Utilized as a probe or building block in the design of chemical tools for studying biological systems.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	2-(1H-Pyrazol-1-Yl)Isonicotinonitrile
CAS No.	956769-58-7
Molecular Formula	C9H6N4
Molecular Weight	170.17 g/mol
Synonyms	2-(1H-Pyrazol-1-yl)isonicotinonitrile; 2-(Pyrazol-1-yl)isonicotinonitrile; 4-Cyano-2-(1H-pyrazol-1-yl)pyridine; 2-(1H-Pyrazol-1-yl)-4-pyridinecarbonitrile; Isonicotinonitrile, 2-(1H-pyrazol-1-yl)-; Pyridine, 4-cyano-2-(1H-pyrazol-1-yl)-
EINECS	Contact for details

Quality Control

Our 2-(1H-Pyrazol-1-Yl)Isonicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.