Description

tert-Butyl 7-Methoxy-4-Oxospiro[Chroman-2,4'-Piperidine]-1'-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and piperidine scaffold. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the discovery and process development of new drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, especially those targeting the central nervous system (CNS) and other specialized therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery programs.
• Process Chemistry Development: Employed in route scouting, optimization, and scale-up studies for the commercial manufacturing of target APIs.
• Synthesis of Biologically Active Molecules: The spiro[chroman-2,4'-piperidine] core is a privileged structure in medicinal chemistry, making this intermediate valuable for creating molecules with potential activity against various disease targets.
• Custom Synthesis & Contract Manufacturing: Supplied to partners requiring a reliable source of this specific, high-quality intermediate for their proprietary synthesis pipelines.

Basic Information

Product Name	tert-Butyl 7-Methoxy-4-Oxospiro[Chroman-2,4'-Piperidine]-1'-Carboxylate
CAS No.	956604-98-1
Molecular Formula	C19H25NO5
Molecular Weight	347.41 g/mol
Synonyms	1'-Boc-7-methoxy-4-oxospiro[chroman-2,4'-piperidine]; tert-Butyl 7-methoxy-4-oxo-1'H-spiro[chromene-2,4'-piperidine]-1'-carboxylate; 7-Methoxy-4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylic acid tert-butyl ester; 1'-tert-Butoxycarbonyl-7-methoxy-4-oxospiro[chroman-2,4'-piperidine]; Boc-7-Methoxy-4-oxospiro[chroman-2,4'-piperidine]; CAS 956604-98-1
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Methoxy-4-Oxospiro[Chroman-2,4'-Piperidine]-1'-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and production. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.