Description

1H-Pyrazole-4-Carbothioamide, 5-Amino-1-Methyl- is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting enzymes and receptors where the pyrazole-thioamide scaffold is pharmacologically relevant.
• Agrochemical Synthesis: Serves as a crucial building block in the design and production of next-generation herbicides, fungicides, and insecticides.
• Ligand in Coordination Chemistry: Utilized in the synthesis of novel metal-organic complexes and catalysts due to its potential chelating properties from the thioamide and amino groups.
• Material Science Research: Investigated as a precursor for the development of organic electronic materials or functional polymers.
• Bioconjugation & Probe Development: Used in chemical biology for creating labeled probes or modifying biomolecules, leveraging its reactive functional groups.

Basic Information

Product Name	1H-Pyrazole-4-Carbothioamide, 5-Amino-1-Methyl-
CAS No.	956534-58-0
Molecular Formula	C5H8N4S
Molecular Weight	156.21 g/mol
Synonyms	5-Amino-1-methyl-1H-pyrazole-4-carbothioamide; 1-Methyl-5-amino-1H-pyrazole-4-carbothioamide; 5-Amino-1-methylpyrazole-4-carbothioamide; 4-Carbothioamide-5-amino-1-methylpyrazole; 956534-58-0; 5-Amino-1-methyl-1H-pyrazole-4-thiocarboxamide
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-4-Carbothioamide, 5-Amino-1-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.