Description

3-Iodo-4-Methoxy-Pyridin-2-Ylamine is a high-value, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures through selective cross-coupling and functionalization reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies and kinase inhibitors.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging its halogen and amine functionality.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials and photoactive compounds.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	3-Iodo-4-Methoxy-Pyridin-2-Ylamine
CAS No.	956485-64-6
Molecular Formula	C6H7IN2O
Molecular Weight	250.04 g/mol
Synonyms	2-Amino-3-iodo-4-methoxypyridine; 4-Methoxy-3-iodopyridin-2-amine; 3-Iodo-4-methoxypyridin-2-amine; 2-Pyridinamine, 3-iodo-4-methoxy-; 956485-64-6; 3-Iodo-4-methoxy-2-aminopyridine; 4-Methoxy-3-iodo-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Methoxy-Pyridin-2-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.