Description

1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-1-[Tris(1-Methylethyl)Silyl]- is a high-value, organosilicon-protected pyrrolopyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its primary commercial value lies in enabling the efficient and selective construction of complex nitrogen-containing heterocycles, which are core scaffolds in modern pharmaceuticals. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for functionalized organic materials and ligands for catalysis.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and medicinal chemistry programs.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-1-[Tris(1-Methylethyl)Silyl]-
CAS No.	956407-32-2
Molecular Formula	C16H25ClN2Si
Molecular Weight	308.92 g/mol
Synonyms	6-Chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1-triisopropylsilyl-1H-pyrrolo[2,3-b]pyridine; 1-Triisopropylsilyl-6-chloro-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1H-pyrrolo[2,3-b]pyridine, 1-(triisopropylsilyl)-; 956407-32-2; TIPS-6-Chloro-7-azaindole; 6-Chloro-1-[(triisopropylsilyl)]-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-1-[Tris(1-Methylethyl)Silyl]- is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.