Description

5-Bromo-2-Methylnicotinonitrile is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a nitrile group, makes it a valuable intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it facilitates key coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, and photoactive materials.
• Chemical Synthesis: Employed in Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to introduce the 5-bromo-2-methylpyridine moiety.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new reaction pathways.

Basic Information

Product Name	5-Bromo-2-Methylnicotinonitrile
CAS No.	956276-47-4
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	5-Bromo-2-methyl-3-cyanopyridine; 3-Cyano-5-bromo-2-methylpyridine; 2-Methyl-5-bromonicotinonitrile; 5-Bromo-2-methylpyridine-3-carbonitrile; 956276-47-4; 5-Bromo-2-methyl-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methylnicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles to meet your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.