Description

2-([(2R,6S)-2,6-Dimethylpiperidin-1-Yl]Methyl)Azepane is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. This compound matters because its unique bicyclic amine structure, featuring a piperidine ring fused to an azepane moiety, serves as a critical building block for constructing complex pharmacologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and receptor modulators.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, especially for neurological and psychiatric disorders.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and medicinal chemistry applications.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study enzyme function and receptor interactions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective synthesis to create enantiomerically pure compounds.
• Agrochemical Research: Potential intermediate in the discovery of new crop protection agents with specific biological activity.
• Academic & Industrial R&D: Fundamental research compound in organic chemistry departments and corporate R&D labs for methodology development and library synthesis.

Basic Information

Product Name	2-([(2R,6S)-2,6-Dimethylpiperidin-1-Yl]Methyl)Azepane
CAS No.	956266-24-3
Molecular Formula	C14H28N2
Molecular Weight	224.39 g/mol
Synonyms	2-[(2R,6S)-2,6-Dimethyl-1-piperidinyl]methyl]azepane; 2-((2R,6S)-2,6-Dimethylpiperidin-1-yl)methyl)azepane; Azepane, 2-[[(2R,6S)-2,6-dimethyl-1-piperidinyl]methyl]-; (2R,6S)-1-[(Azepan-2-yl)methyl]-2,6-dimethylpiperidine; 2-[(2,6-Dimethylpiperidin-1-yl)methyl]azepane (stereoisomer)
EINECS	Contact for details

Quality Control

Our 2-([(2R,6S)-2,6-Dimethylpiperidin-1-Yl]Methyl)Azepane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as chiral purity, chemical purity (by HPLC), and identity confirmation. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.