Description

N'-[1-(3-Chloro-4-Fluorophenyl)-2,5-Dioxopyrrolidin-3-Yl]Pyridine-4-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for constructing molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Used in the research and synthesis of potential inhibitors targeting specific enzyme families.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client research.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	N'-[1-(3-Chloro-4-Fluorophenyl)-2,5-Dioxopyrrolidin-3-Yl]Pyridine-4-Carbohydrazide
CAS No.	956263-25-5
Molecular Formula	C₁₆H₁₂ClFN₄O₃
Molecular Weight	362.74 g/mol
Synonyms	4-Pyridinecarboxylic acid, 2-[1-(3-chloro-4-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]hydrazide; 1-(3-Chloro-4-fluorophenyl)-3-(pyridine-4-carbonylhydrazono)pyrrolidine-2,5-dione; 956263-25-5; N'-[1-(3-Chloro-4-fluorophenyl)-2,5-dioxopyrrolidin-3-ylidene]pyridine-4-carbohydrazide; 3-Hydrazinylidene-1-(3-chloro-4-fluorophenyl)pyrrolidine-2,5-dione pyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Our N'-[1-(1-(3-Chloro-4-Fluorophenyl)-2,5-Dioxopyrrolidin-3-Yl]Pyridine-4-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.