Description

2-(N,N-Dimethylcarboxamido)Phenylboronic Acid Pinacol Ester is a sophisticated organoboron building block, specifically a protected boronic acid derivative, with the CAS registry number 956229-73-5. This compound is valued for its enhanced stability and solubility compared to its free boronic acid counterpart, making it a crucial intermediate in modern synthetic chemistry. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for constructing complex molecules via cross-coupling reactions.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl structures, a common motif in active pharmaceutical ingredients (APIs) and advanced materials.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular architecture is required.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and labeled compounds for studying biological pathways and diagnostics.
• Process Chemistry & Scale-up: Its pinacol ester form offers superior handling characteristics and shelf-life for large-scale manufacturing processes.

Basic Information

Product Name	2-(N,N-Dimethylcarboxamido)Phenylboronic Acid Pinacol Ester
CAS No.	956229-73-5
Molecular Formula	C₁₇H₂₆BNO₃
Molecular Weight	303.21 g/mol
Synonyms	[2-(Dimethylcarbamoyl)phenyl]boronic acid pinacol ester; N,N-Dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 2-(Dimethylcarbamoyl)phenylboronic Acid Pinacol Ester; 2-(N,N-Dimethylaminocarbonyl)phenylboronic Acid Pinacol Ester; Pinacol [2-(Dimethylcarbamoyl)phenyl]boronate; 956229-73-5; B-[2-[(Dimethylamino)carbonyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(N,N-Dimethylcarboxamido)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.