Description

2-tert-Butoxycarbonylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical, air-stable building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular architecture is crucial.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.
• Academic & R&D Laboratories: A staple reagent for methodological development in organic synthesis and catalysis studies.
• Scale-up Process Chemistry: Its stability makes it suitable for transitioning from milligram-scale discovery to kilogram-scale pilot production.

Basic Information

Product Name	2-tert-Butoxycarbonylphenylboronic Acid Pinacol Ester
CAS No.	956229-69-9
Molecular Formula	C₁₇H₂₅BO₄
Molecular Weight	304.19 g/mol
Synonyms	2-((tert-Butoxycarbonyl)phenyl)boronic acid pinacol ester; Boc-Protected Phenylboronic Acid Pinacol Ester; (2-((tert-Butoxycarbonyl)phenyl)boronic acid, pinacol ester; tert-Butyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-Boc-phenylboronic acid pinacol ester; Boc-2-Bpin-benzoic acid (informal); CAS 956229-69-9
EINECS	Contact for details

Quality Control

Our 2-tert-Butoxycarbonylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.