Description

5-Chloro-2,3-Dihydrospiro[Indene-1,3'-Pyrrolidine] is a high-value, spirocyclic organic compound that serves as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique fused-ring structure makes it a versatile building block for constructing complex molecular architectures with potential biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs), particularly within therapeutic areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Biology Probes: Serves as a core scaffold for developing molecular probes to study biological pathways and protein interactions.
• Agrochemical Synthesis: Potential intermediate in the development of advanced pesticides and herbicides with novel modes of action.
• Material Science Precursor: Can be utilized in the synthesis of specialized organic materials and ligands for catalysis.

Basic Information

Product Name	5-Chloro-2,3-Dihydrospiro[Indene-1,3'-Pyrrolidine]
CAS No.	956141-91-6
Molecular Formula	C12H14ClN
Molecular Weight	207.70 g/mol
Synonyms	5-Chloro-2,3-dihydrospiro[indene-1,3'-pyrrolidine]; 5-Chloro-2,3-dihydro-1H-spiro[indene-1,3'-pyrrolidine]; 5-Chlorospiro[indane-1,3'-pyrrolidine]; 5-Chloro-1'H-spiro[indene-1,3'-pyrrolidine]; 956141-91-6; Spiro[indene-1,3'-pyrrolidine], 5-chloro-2,3-dihydro-; 5-Chloro-2,3-dihydrospiro[indene-1,3'-pyrrolidine] HCl salt (if applicable)
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,3-Dihydrospiro[Indene-1,3'-Pyrrolidine] is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.