Description

5-Bromo-2,3-Dihydrospiro[Indene-1,3'-Pyrrolidine is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules and drug candidates. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Spirocyclic Compound Synthesis: Serves as a core scaffold for constructing spirocyclic frameworks, which are prized in drug discovery for their three-dimensionality and potential to improve drug-like properties.
• Ligand and Receptor Probe Development: Employed in the creation of chemical probes for studying biological targets and pathways.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.
• Pre-clinical Development: Supports the production of compounds for pharmacological evaluation and toxicology studies.

Basic Information

Product Name	5-Bromo-2,3-Dihydrospiro[Indene-1,3'-Pyrrolidine
CAS No.	956141-86-9
Molecular Formula	C12H14BrN
Molecular Weight	252.15 g/mol
Synonyms	5-Bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine]; 5-Bromo-2,3-dihydro-1H-spiro[indene-1,3'-pyrrolidine]; 5-Bromospiro[indane-1,3'-pyrrolidine]; Spiro[indane-1,3'-pyrrolidine], 5-bromo-; 956141-86-9; 5-Bromo-spiro[indane-1,3'-pyrrolidine]; 5-Bromo-1'H-spiro[indene-1,3'-pyrrolidine]
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Dihydrospiro[Indene-1,3'-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.