Description

2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-((2-(Trimethylsilyl)Ethoxy)Methyl)-3H-Imidazo[4,5-B]Pyridine is a high-value, multi-functional heterocyclic building block containing both a protected boronic ester and a SEM-protected nitrogen. This compound is critical for enabling complex cross-coupling reactions, particularly in the synthesis of advanced pharmaceutical intermediates and functional materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex heterocyclic cores.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tool compounds for biological target identification and validation.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research within academic and CRO settings.
• Scale-up Process Development: Supports process chemistry teams in optimizing routes for the commercial-scale production of fine chemicals.

Basic Information

Product Name	2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-((2-(Trimethylsilyl)Ethoxy)Methyl)-3H-Imidazo[4,5-B]Pyridine
CAS No.	956034-65-4
Molecular Formula	C19H32BN3O3Si
Molecular Weight	389.37 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-3-((2-(trimethylsilyl)ethoxy)methyl)-3H-imidazo[4,5-b]pyridine; 2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazo[4,5-b]pyridine; SEM-Protected Imidazopyridine Boronic Ester; 956034-65-4; 3H-Imidazo[4,5-b]pyridine, 2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-[[2-(trimethylsilyl)ethoxy]methyl]-
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-((2-(Trimethylsilyl)Ethoxy)Methyl)-3H-Imidazo[4,5-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.