Description

3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Indazole is a high-value, multi-functional chemical building block designed for advanced synthetic applications. This compound is critical for enabling complex molecular construction, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for cross-coupling reactions and targeted molecular modifications.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel indazole-based drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, leveraging the indazole core for biological activity.
• Material Science: Serves as a building block for creating organic electronic materials, such as OLED emitters or charge transport layers.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biochemical and pharmacological studies.
• Process Chemistry & Scale-up: Suitable for route scouting and optimization from milligram to kilogram scale in process R&D laboratories.
• Academic & Institutional Research: A valuable reagent for methodology development in organic synthesis and catalysis research at universities and institutes.

Basic Information

Product Name	3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Indazole
CAS No.	956006-15-8
Molecular Formula	C20H33BN2O3Si
Molecular Weight	388.39 g/mol
Synonyms	1-((2-(Trimethylsilyl)ethoxy)methyl)-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-3-methyl-1H-indazole; 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-yl)methoxy)ethyl)trimethylsilane; 956006-15-8; SEM-Protected 3-Methyl-5-Boronic Acid Pinacol Ester Indazole; 3-Methyl-5-Bpin-1-SEM-Indazole
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.