Description

1H-Indole-6-Carbonitrile, 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional boronic ester derivative of indole, serving as a critical synthetic intermediate. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and advanced materials chemistry. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and the creation of organic electronic materials who require precise, scalable building blocks for complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional organic electronic materials.
• Chemical Research: A versatile reagent for academic and industrial R&D labs exploring new C-C bond formation methodologies and heterocyclic chemistry.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	1H-Indole-6-Carbonitrile, 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	955979-23-4
Molecular Formula	C15H17BN2O2
Molecular Weight	268.12 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-6-carbonitrile; 4-BPin-1H-indole-6-carbonitrile; 6-Cyano-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-6-carbonitrile; 1H-Indole-6-carbonitrile, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 955979-23-4; BPin-indole-carbonitrile derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed batch-specific data are available upon request. We adhere to a quality management system designed to meet the stringent requirements of research and development as well as scale-up manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.