Description

Methyl 2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial advanced pharmaceutical intermediate and building block in modern organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise and reliable boron-containing synthons for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring biaryl or substituted aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate specific aromatic boron functionalities.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its boronate group enables precise molecular engineering.
• Suzuki-Miyaura Cross-Coupling: Acts as a stable, air-handleable boronate reagent for palladium-catalyzed carbon-carbon bond formation, a cornerstone reaction in medicinal and process chemistry.
• Chemical Research & Development: Serves as a versatile synthon in academic and industrial R&D labs for exploring new synthetic methodologies and creating complex organic molecules.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Methyl 2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	955929-54-1
Molecular Formula	C15H21BO4
Molecular Weight	276.14 g/mol
Synonyms	2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylbenzoate; 3-Pinacolatoboryl-2-methylbenzoic acid methyl ester; 2-Methyl-3-(pinacolatoboryl)benzoic acid methyl ester; Methyl 2-methyl-3-(pinacolatoboryl)benzoate; 955929-54-1; Benzoic acid, 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the original container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.