Description

Methyl 3,5-Difluoropyridine-2-Carboxylate is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a difluoropyridine core and a methyl ester group, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized heterocycles for organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 3,5-Difluoropyridine-2-Carboxylate
CAS No.	955885-64-0
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3,5-difluoro-, methyl ester; Methyl 3,5-difluoropicolinate; 3,5-Difluoropyridine-2-carboxylic acid methyl ester; Methyl 3,5-difluoro-2-pyridinecarboxylate; Picolinic acid, 3,5-difluoro-, methyl ester; 3,5-Difluoro-2-(methoxycarbonyl)pyridine; MFCD11871103
EINECS	Contact for details

Quality Control

Our Methyl 3,5-Difluoropyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly sealed due to the compound's sensitivity to moisture and potential reactivity with strong alkalis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.