Description

1,3,2-Dioxaborolane, 2,2-[2,2-Bis(Methoxymethoxy)[1,1-Binaphthalene]-3,3-Diyl]Bis[4,4,5,5-Tetramethyl- is a sophisticated, high-purity organoboron compound, specifically a functionalized binaphthyl-derived boronic ester. This chemical is a critical chiral ligand precursor and building block in advanced organic synthesis and catalysis. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers developing novel asymmetric catalysts and active pharmaceutical ingredients (APIs).

Application

• Asymmetric Catalysis: Serves as a key chiral ligand precursor for transition metal catalysts used in enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate: A high-value building block in the multi-step synthesis of complex, chiral drug molecules, particularly in oncology and CNS therapeutic areas.
• Material Science Research: Used in the development of chiral organic frameworks (COFs), polymers, and advanced functional materials with specific optical properties.
• Cross-Coupling Reactions: Functions as an air-stable, protected boronic acid equivalent in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for the discovery of new synthetic pathways.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2,2-[2,2-Bis(Methoxymethoxy)[1,1-Binaphthalene]-3,3-Diyl]Bis[4,4,5,5-Tetramethyl-
CAS No.	955405-38-6
Molecular Formula	C40H46B2O8
Molecular Weight	676.41 g/mol
Synonyms	(R)-3,3'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; (S)-3,3'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; BINOL-Derived Diboronic Ester; 2,2'-[2,2'-Bis(methoxymethoxy)[1,1'-binaphthalene]-3,3'-diyl]bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); MOM-Protected BINOL Boronic Ester; 3,3'-Diboronic Acid BINOL Derivative (Protected); (R)- and (S)-MOM-BINOL-Bis(pinacol boronate)
EINECS	Contact for details

Quality Control

Our high-purity organoboron compounds are manufactured under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess (where applicable) meet rigorous internal specifications. Standard analytical techniques including HPLC, NMR (1H, 13C, 11B), and Chiral HPLC are employed. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee (R or S isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.