Description

4-Chloro-2-Methoxy-5-Nitropyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Serves as a versatile precursor in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to synthesize complex pyridine-based ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as electron-transport layers and photoactive compounds.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and labeling agents used in biochemical research.
• Custom Synthesis and Scale-up: Available for contract research organizations (CROs) and CDMOs for custom synthesis projects from gram to multi-kilogram scale.

Basic Information

Product Name	4-Chloro-2-Methoxy-5-Nitropyridine
CAS No.	955395-98-9
Molecular Formula	C6H5ClN2O3
Molecular Weight	188.57 g/mol
Synonyms	5-Nitro-4-chloro-2-methoxypyridine; 2-Methoxy-4-chloro-5-nitropyridine; 4-Chloro-2-methoxy-5-nitropyridine; 4-Chloro-5-nitro-2-methoxypyridine; Pyridine, 4-chloro-2-methoxy-5-nitro-; 955395-98-9
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methoxy-5-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.