Description

(2-Pyrrolidin-1-Ylpyrimidin-5-Yl)Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those containing pyrimidine and pyrrolidine motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boronic acid reagent for forming carbon-carbon bonds in medicinal chemistry and materials science research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and tools for studying biological systems and target validation.
• Materials Science: Potential building block for creating novel organic electronic materials and metal-organic frameworks (MOFs).
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.

Basic Information

Product Name	(2-Pyrrolidin-1-Ylpyrimidin-5-Yl)Boronic Acid
CAS No.	955374-13-7
Molecular Formula	C10H14BN3O2
Molecular Weight	219.05 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(pyrrolidin-1-yl)pyrimidine; 2-(1-Pyrrolidinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; (2-(Pyrrolidin-1-yl)pyrimidin-5-yl)boronic acid, pinacol ester; 2-Pyrrolidin-1-yl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrimidine; B-[2-(1-Pyrrolidinyl)-5-pyrimidinyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of (2-Pyrrolidin-1-Ylpyrimidin-5-Yl)Boronic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.