Description

3-Bromo-5-Fluoro-4-Pyridinecarboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated pyridine core, which facilitates selective cross-coupling reactions and serves as a key precursor in the development of complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its aromatic and modifiable carboxylic acid group.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-5-Fluoro-4-Pyridinecarboxylic Acid
CAS No.	955372-86-8
Molecular Formula	C6H3BrFNO2
Molecular Weight	219.99 g/mol
Synonyms	4-Pyridinecarboxylic acid, 3-bromo-5-fluoro-; 3-Bromo-5-fluoropyridine-4-carboxylic acid; 5-Fluoro-3-bromopyridine-4-carboxylic acid; 3-Bromo-5-fluoro-4-carboxypyridine; 3-Br-5-F-4-PyCOOH; 955372-86-8; 3-Bromo-5-fluoroisonicotinic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-4-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to prevent degradation from ambient moisture and light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.