Description

4-Pivalamidopyridine-3-Boronic Acid is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex heterocyclic structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl systems under mild conditions.
• Ligand and Catalyst Development: Employed in the creation of novel pyridine-based ligands for transition metal catalysis.
• Material Science Research: A building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.

Basic Information

Product Name	4-Pivalamidopyridine-3-Boronic Acid
CAS No.	955123-29-2
Molecular Formula	C11H15BN2O3
Molecular Weight	234.07 g/mol
Synonyms	3-Borono-4-pivalamidopyridine; 4-(Pivalamido)pyridine-3-boronic acid; (4-(2,2-Dimethylpropanamido)pyridin-3-yl)boronic acid; 4-Pivalamido-3-pyridineboronic acid; PINAP-Boronic Acid (derivative); 3-Pyridineboronic acid, 4-[(2,2-dimethyl-1-oxopropyl)amino]-; Boronic acid, B-[4-[(2,2-dimethyl-1-oxopropyl)amino]-3-pyridinyl]-
EINECS	Contact for details

Quality Control

Our 4-Pivalamidopyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere for long-term stability. The compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (H-NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.