Description

2-Pyridinecarboxaldehyde, 5-(Difluoromethyl)- is a specialized pyridine derivative featuring a difluoromethyl substituent, a structural motif of significant interest in modern synthetic chemistry. This compound serves as a versatile and high-value building block for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector to create novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting neurological disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Ligand Synthesis: Serves as a starting material for creating novel chelating ligands and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Fluorinated Building Block: Essential for introducing fluorine atoms into target molecules to modulate their physicochemical properties, such as lipophilicity and metabolic stability.
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.

Basic Information

Item	Detail
Product Name	2-Pyridinecarboxaldehyde, 5-(Difluoromethyl)-
CAS No.	955112-64-8
Molecular Formula	C7H5F2NO
Molecular Weight	157.12 g/mol
Synonyms	5-(Difluoromethyl)pyridine-2-carboxaldehyde; 5-(Difluoromethyl)-2-pyridinecarboxaldehyde; 5-(Difluoromethyl)picolinaldehyde; 2-Pyridinecarboxaldehyde, 5-(difluoromethyl)-; 5-Difluoromethyl-pyridine-2-carbaldehyde; 5-(Difluoromethyl)-2-formylpyridine; 2-Formyl-5-(difluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxaldehyde, 5-(Difluoromethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.