Description

3-Hydroxy-4-Methylpiperidine Hydrochloride is a high-purity, functionalized piperidine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its unique stereochemistry and functional group compatibility, enabling the construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, receptor modulators, and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Catalyst & Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: A versatile building block in medicinal chemistry and process chemistry for exploring new chemical entities and optimizing synthetic routes.
• Custom Synthesis: Employed in contract research and manufacturing (CRAM) for the custom production of complex, high-value specialty chemicals.

Basic Information

Product Name	3-Hydroxy-4-Methylpiperidine Hydrochloride
CAS No.	955028-85-0
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	4-Methyl-3-piperidinol hydrochloride; 3-Hydroxy-4-methylpiperidine HCl; 4-Methylpiperidin-3-ol hydrochloride; 3-Piperidinol, 4-methyl-, hydrochloride; (3R,4S)-3-Hydroxy-4-methylpiperidine hydrochloride (for stereoisomers); 4-Methyl-3-hydroxypiperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-4-Methylpiperidine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (for specific isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.