Description

3-Piperidinol, 4-Methyl-, Hydrochloride (1:1), (3R,4R)-Rel-(+)- is a high-purity chiral piperidine derivative, a crucial building block in modern pharmaceutical synthesis. Its defined stereochemistry and hydrochloride salt form offer superior stability and handling for the development of enantiomerically pure active pharmaceutical ingredients (APIs). This compound is essential for research and production chemists in the pharmaceutical and fine chemical industries, particularly for creating novel therapeutics with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Serves as a building block for developing novel, stereospecific pesticides and herbicides.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and enzyme inhibitors for target validation studies.
• Material Science: Potential precursor for chiral ionic liquids or advanced polymers with specific optical properties.
• Academic & Contract Research: A valuable reagent for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	3-Piperidinol, 4-Methyl-, Hydrochloride (1:1), (3R,4R)-Rel-(+)-
CAS No.	955028-77-0
Molecular Formula	C6H14ClNO
Molecular Weight	151.64 g/mol
Synonyms	(3R,4R)-4-Methylpiperidin-3-ol hydrochloride; (+)-rel-(3R,4R)-4-Methyl-3-piperidinol hydrochloride; 4-Methyl-3-piperidinol hydrochloride, (3R,4R)-rel-(+)-; (3R,4R)-rel-4-Methyl-3-piperidinol hydrochloride; 3-Hydroxy-4-methylpiperidine hydrochloride; 4-Methyl-3-piperidinol HCl; (3R*,4R*)-4-Methylpiperidin-3-ol hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Piperidinol, 4-Methyl-, Hydrochloride (1:1), (3R,4R)-Rel-(+)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.