Description

trans-4-(Hydroxymethyl)-3-Piperidinol Hydrochloride is a high-purity, functionalized piperidine derivative offered as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its dual hydroxyl functionality. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its piperidine scaffold for biological activity.
• Chemical Research & Development: Serves as a versatile building block for constructing complex nitrogen-containing heterocycles and ligands for catalysis.
• Process Chemistry: Employed in scale-up and optimization studies for the production of fine chemicals and active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for methodological studies in asymmetric synthesis and medicinal chemistry.

Basic Information

Product Name	trans-4-(Hydroxymethyl)-3-Piperidinol Hydrochloride
CAS No.	955028-06-5
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	trans-3-Hydroxy-4-(hydroxymethyl)piperidine hydrochloride; (3R,4S)-3-Hydroxy-4-(hydroxymethyl)piperidine hydrochloride; (3S,4R)-3-Hydroxy-4-(hydroxymethyl)piperidine hydrochloride; 4-(Hydroxymethyl)piperidin-3-ol hydrochloride; 3-Piperidinol, 4-(hydroxymethyl)-, hydrochloride, (3R,4S)-rel-; 955028-06-5; trans-4-Hydroxymethyl-3-piperidinol HCl
EINECS	Contact for details

Quality Control

Our trans-4-(Hydroxymethyl)-3-Piperidinol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.