Description

Methyl 4-Iodo-2-(Trifluoromethyl)Benzoate is a high-purity, multi-functional aromatic ester building block designed for advanced chemical synthesis. Its unique structure, featuring both an iodine substituent and a trifluoromethyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drug candidates for oncology, CNS, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The aryl iodide moiety is a versatile handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) to create complex biaryl and conjugated systems.
• Chemical Research & Development: A valuable reagent in medicinal chemistry and process R&D for structure-activity relationship (SAR) studies and lead optimization.
• Fluorine Chemistry: Acts as a standardized source of a specific trifluoromethylbenzene motif for studying fluorine's effects on molecular properties.

Basic Information

Product Name	Methyl 4-Iodo-2-(Trifluoromethyl)Benzoate
CAS No.	954815-14-6
Molecular Formula	C9H6F3IO2
Molecular Weight	330.04 g/mol
Synonyms	Methyl 4-iodo-2-(trifluoromethyl)benzoate; Benzoic acid, 4-iodo-2-(trifluoromethyl)-, methyl ester; 4-Iodo-2-(trifluoromethyl)benzoic acid methyl ester; Methyl 4-iodo-α,α,α-trifluoro-o-toluate; 2-(Trifluoromethyl)-4-iodobenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Iodo-2-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.