Description

1-(4-Aminopiperidin-1-Yl)-3,3-Dimethylbutan-1-One is a high-purity, specialized piperidine derivative building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores and optimize lead compounds.
• Agrochemical Synthesis: Intermediate in the development of new pesticides, herbicides, and plant growth regulators requiring specific amine functionalities.
• Fine Chemical Production: Serves as a precursor for synthesizing complex specialty chemicals, catalysts, and ligands used in asymmetric synthesis.
• Bioconjugation & Probe Development: The reactive amine group enables its use in creating biochemical probes, diagnostic agents, and antibody-drug conjugates (ADCs).
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	1-(4-Aminopiperidin-1-Yl)-3,3-Dimethylbutan-1-One
CAS No.	954575-08-7
Molecular Formula	C11H22N2O
Molecular Weight	198.31 g/mol
Synonyms	1-(4-Aminopiperidin-1-yl)-3,3-dimethylbutan-1-one; 3,3-Dimethyl-1-(4-aminopiperidin-1-yl)butan-1-one; 4-Amino-1-(3,3-dimethylbutanoyl)piperidine; 1-(4-Amino-1-piperidinyl)-3,3-dimethyl-1-butanone; tert-Butylacetyl-4-aminopiperidine; N-(3,3-Dimethylbutanoyl)-4-aminopiperidine
EINECS	Contact for details

Quality Control

Our 1-(4-Aminopiperidin-1-Yl)-3,3-Dimethylbutan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.