Description

3-Pyridinecarboxylic Acid, 5-Chloro-6-Ethoxy- is a high-purity, functionalized pyridine derivative serving as a critical synthetic intermediate. Its unique halogenated and alkoxylated structure makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its halogen and ether functionalities.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probe Development: Utilized to synthesize molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A pivotal starting material for custom synthesis houses and CDMOs producing complex, multi-step organic compounds for clients.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 5-Chloro-6-Ethoxy-
CAS No.	954277-71-5
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	5-Chloro-6-ethoxynicotinic Acid; 5-Chloro-6-ethoxypyridine-3-carboxylic Acid; 3-Carboxy-5-chloro-6-ethoxypyridine; 6-Ethoxy-5-chloronicotinic Acid; 5-Chloro-6-ethoxy-3-pyridinecarboxylic Acid; 954277-71-5; 5-Chloro-6-ethoxy-nicotinic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarboxylic Acid, 5-Chloro-6-Ethoxy- is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its acidic nature, keep away from strong bases, oxidizing agents, and incompatible materials. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.