Description

6-(4-Propylpiperazin-1-Yl)Pyridin-3-Amine CAS NO 954251-17-3 is a high-purity, advanced pharmaceutical intermediate featuring a pyridine core substituted with a propylpiperazine amine group. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where precise chemical structure and reliable purity are paramount for successful outcomes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially for neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs targeting specific receptors (e.g., serotonin, dopamine receptors).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in pharmacological assays to study receptor binding and enzyme inhibition mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production of clinical trial materials and commercial APIs.

Basic Information

Product Name	6-(4-Propylpiperazin-1-Yl)Pyridin-3-Amine
CAS No.	954251-17-3
Molecular Formula	C12H20N4
Molecular Weight	220.32 g/mol
Synonyms	6-(4-Propyl-1-piperazinyl)-3-pyridinamine; 3-Amino-6-(4-propylpiperazin-1-yl)pyridine; 6-(4-Propylpiperazin-1-yl)pyridin-3-amine; 954251-17-3; 6-(4-n-Propylpiperazin-1-yl)pyridin-3-amine; 3-Pyridinamine, 6-(4-propyl-1-piperazinyl)-; 6-(4-propylpiperazin-1-yl)-3-aminopyridine
EINECS	Contact for details

Quality Control

Our production of 6-(4-Propylpiperazin-1-Yl)Pyridin-3-Amine adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all critical quality attributes to ensure the material meets the exacting standards required for pharmaceutical R&D and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.